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Whether you are dealing with rheumatoid arthritis (RA), psoriatic arthritis (PsA), lupus (SLE), Sjögren’s disease (SD), or even osteoarthritis (OA), chronic inflammation keeps the immune system in a constant “attack mode,” leading to: Pain Swelling Stiffness Mobility problems Tissue and cartilage damage This chronic, ongoing inflammation not only makes joints hurt more, but it will worsen blood sugar control, fatigue, brain fog, and increase the risk of heart disease

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Clinical effects of short-term oral budesonide on the hypothalamic-pituitary-adrenal axis in dogs with inflammatory bowel disease